Arthrosamid® Injection for
Knee Osteoarthritis
Harley Street, London | Led by Professor Paul Y.F. Lee
Arthrosamid® (a registered trademark of Contura A/S.).
Relief & Protect
Arthrosamid® at London Cartilage Clinic
Treatment at a glance
- Location
- 66 Harley Street, London
- Treatment
- Ultrasound-guided Arthrosamid® knee injection
- Best suited for
- Selected patients with knee osteoarthritis
- Led by
- Professor Paul Y.F. Lee
- Price
- From £3,000One box. See cost guide for two/three-box pricing.
- Includes
- Consultation, ultrasound, injection, protocol, six-week follow-up
- Access
- Self-funded private treatment (not NHS or PMI)
- Next step
- Free discovery call or suitability assessment
Am I Suitable?
Take the Arthrosamid® Suitability Assessment
Eight quick questions to support a shared decision-making conversation about Arthrosamid®. Your answers stay with you across visits, so you can pick up where you left off.
Will Arthrosamid work for me?
Arthrosamid® suitability questionnaire
Completed 0/8
Question 1 of 8
How old are you?
Older age associated with higher odds of benefit in your cohort.
Please select an option before moving to the next question.
The UK Authority in Arthrosamid®
Knee Injection
Arthrosamid® is a long-acting injection used to manage symptoms of knee osteoarthritis.
In London, Arthrosamid® treatment is led by Professor Paul Y.F. Lee, Consultant Orthopaedic Surgeon, medical engineer, and recognised UK authority in joint preservation and regenerative-aware knee care.
Professor Lee was the first clinician to perform Arthrosamid® knee injections in the UK and has developed a specialist, experience-led protocol based on large-volume clinical practice.
What Is Arthrosamid®?
Arthrosamid® is made from a polyacrylamide hydrogel, a non-biodegradable, biocompatible material designed to remain inside the knee joint.
Unlike steroid or hyaluronic acid injections, Arthrosamid®:
- Is not absorbed by the body
- Remains in the joint long-term
- Acts as a mechanical cushion
- Symptom improvement lasting months
It does not regenerate cartilage and is not a cure for arthritis.
How Arthrosamid® Works
in the Knee
Inside the joint, Arthrosamid®:
- Improves joint lubrication
- Reduces mechanical stress on damaged cartilage
- Enhances shock absorption
- Helps reduce pain, stiffness, and functional limitation
It is best considered a joint-preserving treatment, helping patients remain active and delay more invasive surgery when appropriate.
Who Arthrosamid® Is
Best Suited For
Arthrosamid® is not a routine injection. Outcomes depend heavily on patient selection.
You may be a good candidate if:
You have mild to moderate knee osteoarthritis
You are middle-aged or older
You do not have diabetes
Both knees are symptomatic and being treated
You want improvement, not complete cure
Your goal is to delay knee replacement, not necessarily avoid it forever
We assess suitability using a structured Arthrosamid® suitability framework, developed from clinical data and patient outcomes.
When Arthrosamid® May
Be Less Suitable
Arthrosamid® may be less effective if:
Your arthritis is advanced or bone-on-bone
The knee is severely unstable or deformed
You are already close to needing knee replacement
You expect a single injection to 'fix' the knee completely
Honest Clinical Advice
In these cases, benefit may be limited or temporary, and alternatives are discussed openly to ensure you receive the most appropriate care for your specific condition.
Independent Clinical
Study Experience
Our use of Arthrosamid® is informed by an independent, clinician-led clinical study, not sponsored by the manufacturer.
This allows us to give real-world, balanced advice, rather than relying on promotional claims.
Choosing Where To Have Arthrosamid®
Why choose London Cartilage Clinic
for Arthrosamid®?
Seven things that distinguish Arthrosamid® at London Cartilage Clinic from a generic injection appointment.
Experienced Arthrosamid® team
Professor Paul Lee was the first clinician to perform Arthrosamid® knee injections in the UK and has now treated over 600 patients. Our team has more Arthrosamid® cases on the published outcome database than any other UK provider.
Meet Professor LeeConsultant-led assessment
Every patient is assessed by Professor Lee in person. The clinician you see at consultation is the clinician who delivers the injection. No hand-off to a less experienced operator.
Who is suitable?Ultrasound-guided treatment
Every Arthrosamid® injection is delivered under real-time ultrasound guidance, not by anatomical landmark alone. Accurate intra-articular placement is fundamental to the result.
How treatment worksIndependent clinical study experience
We publish real-world outcome data from over 600 treated patients. This informs suitability decisions before treatment and sets realistic expectations afterwards.
See the evidenceConservative safety protocol
A deliberately conservative infection-prevention protocol, including routine IV antibiotic cover and sterile technique standards above the typical outpatient norm.
Infection protocolClear self-funded pricing
Fixed pricing from £3,000, inclusive of consultation, ultrasound, the product, the protocol and the six-week follow-up. No surprise add-ons.
See Arthrosamid costFollow-up and rehabilitation
Six-week clinical review included as standard, with onward physiotherapy guidance and a direct line to the team during recovery. Aftercare is part of the treatment, not an add-on.
Free discovery call
Safety First: Why Our London Protocol Is Different
Professor Paul Y.F. Lee has now:
Personally performed
Arthrosamid® injections
Led a clinical group with
injections
Key safety principles include:
Intravenous (IV) antibiotics for every injection
No oral antibiotics (due to variable absorption)
Ultrasound-guided intra-articular placement
Enhanced sterile technique
A bespoke injection “cocktail”, developed internally
Some aspects of this protocol are intentionally not shared, as they form part of our internal safety practice.
Are all Arthrosamid
Injections the Same?
Not all clinics provide the same level of care. Professor Paul Lee at the London Cartilage Clinic explains why technique, precision, and clinical experience are the deciding factors in your treatment outcome.
Precision Guided
Every injection is administered using advanced ultrasound guidance to ensure 100% accuracy within the joint capsule.
Specialist Led
Treatment is overseen by multi-disciplinary experts specialising in cartilage repair and joint preservation.
Tailored Aftercare
Beyond the injection, we provide a bespoke rehabilitation protocol to maximize your long-term mobility.
Harley Street Excellence
Access world-class clinical facilities in the heart of London’s premier medical district.
Infection Risk &
Important Context
Infection is a risk with any joint injection.
With Arthrosamid®, infection is a particularly serious issue because the material is permanent.
Historical Complications in Literature:
There are published medical papers describing complications from related polyacrylamide hydrogel products (often under the name Aquamid), mainly relating to:
- Cosmetic soft-tissue injections
- Large volumes
- Non-joint use
These are not directly comparable to modern, image-guided knee injections, but they are important context and are discussed openly. Patients who wish to read this literature can be directed to the paper.
Clinical Longevity & Performance
Comparing Arthrosamid® with traditional knee injection protocols to help you make an informed clinical decision.
Arthrosamid®
Typical Duration
Up to 2 Years
Relief Type
Long-term
Key Considerations
- Non-biodegradable single injection
- Requires specialist safety protocols
PRP Therapy
BiologicalMixed clinical evidence regarding long-term efficacy.
Hyaluronic Acid
LubricationTemporary symptom relief, variable benefit.
Steroid Injection
Anti-inflammatoryShort-term acute relief only.
*Duration of efficacy varies by individual patient factors, severity of osteoarthritis, and clinical indications. Please consult with our medical team for a personalised assessment.
Arthrosamid® Treatment in Harley Street, London
Arthrosamid® injections are performed by Professor Paul Y.F. Lee at specialist clinics in Harley Street, London.
All patients undergo:
- Consultant-led assessment
- Imaging review (X-ray ± MRI)
- Arthrosamid® suitability assessment
- Shared decision-making discussion
Patients are referred nationally and internationally for Professor Lee’s experience in complex knee osteoarthritis and joint preservation.
Is Arthrosamid® Right for You?
Arthrosamid® can be an excellent option for the right patient, but it requires:
If these principles align with your goals, Arthrosamid® may be appropriate.
Common Questions About Arthrosamid®
Frequently asked questions
Six of the most common questions patients ask about Arthrosamid®. For the full patient FAQ, see the full Arthrosamid® patient FAQ.
How much does Arthrosamid cost in the UK?
Arthrosamid at London Cartilage Clinic costs from £3,000 for one box, £5,500 for two boxes, or £8,000 for three boxes. Each price is inclusive of consultation, ultrasound, the Arthrosamid product, the published fifteen-step injection protocol and a six-week follow-up. Most patients are treated with one box per joint. See the Arthrosamid cost guide for full pricing detail.
Is Arthrosamid available on the NHS?
No. Arthrosamid is not routinely funded by the NHS and is not currently covered by major UK private medical insurers, including Bupa and AXA. Patients access Arthrosamid privately on a self-funded basis. Read the full Arthrosamid funding and insurance guide.
Does Arthrosamid really work?
Published outcome data for Arthrosamid in knee osteoarthritis shows on average two to three years of symptom relief from a single injection in suitable patients. Individual outcomes vary by stage of arthritis, body weight and activity level, and not every patient is a candidate. See the Arthrosamid clinical evidence page for our real-world outcome data from over 600 treated patients.
What are the risks of Arthrosamid?
Reported side effects include short-term injection-site pain, swelling and stiffness. The most serious risk is joint infection, which is rare but warrants a conservative prevention protocol. London Cartilage Clinic uses ultrasound guidance, sterile technique and routine IV antibiotic cover. See side effects and safety and infection risk and prevention for the full picture.
How long does Arthrosamid last?
Published outcome data for the knee shows symptom relief lasting on average two to three years from a single Arthrosamid injection, with continued benefit established by twelve weeks. Most patients begin to notice improvement at four to six weeks. Arthrosamid is a long-acting cushion, not a regenerative treatment, and is not a cure for arthritis.
Who performs Arthrosamid treatment at London Cartilage Clinic?
Arthrosamid at London Cartilage Clinic is delivered by Professor Paul Y.F. Lee, Consultant Orthopaedic Surgeon. Professor Lee was the first clinician to perform Arthrosamid knee injections in the UK and developed the published fifteen-step injection protocol used at London Cartilage Clinic.
Book an Arthrosamid® Assessment – London
Long-lasting relief starts with the right decision — not just an injection.
Learn More about Arthrosamid
Deep dive into our clinical resources and patient guides.
Cost in the UK
Arthrosamid® cost in the UK from £3,000, what is included and why prices vary.
NHS & Insurance
Is Arthrosamid® available on the NHS or private insurance?
Suitability
Who is suitable for Arthrosamid® — and who may need caution.
Clinical Evidence
Real-world outcome data and what the evidence means for patients.
Side Effects & Safety
Arthrosamid® side effects, risks, complications and clinical context.
Infection Risk
Arthrosamid® infection risk, prevention protocol and IV antibiotic policy.
In London
Private Arthrosamid® treatment at our Harley Street clinic.
Self-Assessment
Eight-question Arthrosamid® suitability self-assessment tool.
Full FAQ
Arthrosamid® patient FAQ across cost, suitability, safety and comparisons.
vs Hyaluronic Acid
Arthrosamid® compared to hyaluronic acid injections.
vs PRP
Arthrosamid® compared to PRP for knee osteoarthritis.
vs Steroid Injection
Arthrosamid® compared to corticosteroid injection.
vs Knee Replacement
Where Arthrosamid® may help delay surgery — and where it cannot.
Arthrosamid® Injection
Comprehensive Overview
Arthrosamid® is a registered trademark of Contura A/S. London Cartilage Clinic is not affiliated with or endorsed by Contura A/S.