Cartilage specialists for Regeneration, Repair & Replacement

Comprehensive care for cartilage, meniscus and ACL injury, offering advanced injections, regenerative techniques and specialist surgical expertise.

Specialist Focus Areas

Focused Expertise

Providing advanced biological and surgical solutions for complex joint conditions.

Cartilage Regeneration

Cartilage Regeneration

Surgical & Non-surgical options

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Meniscus Repair

Meniscus Repair

Surgical & Non-surgical options

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ACL Repair

ACL Repair

Surgical Repair & Reconstruction

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Professor Paul Lee

Specialist Care at 66 Harley Street

Based in London’s prestigious Harley Street medical district, London Cartilage Clinic is a dedicated centre for the assessment and treatment of cartilage damage.

Led by Professor Paul Lee, our clinic specialises in cartilage and joint preservation, offering advanced, evidence-based solutions for patients seeking reliable alternatives to conventional healthcare pathways — without lengthy waiting times.

Our approach is informed by Musculoskeletal Regeneration Medicine, an interdisciplinary clinical framework combining orthopaedics, engineering, and regenerative science, and is tailored to both sports-related cartilage injuries and degenerative joint conditions.

Our Expertise

Non-Surgical Services

Chondrofiller treatment

Chondrofiller

London Cartilage Clinic is currently the only centre in the UK offering Chondrofiller®, an advanced treatment designed for focal cartilage defects in the knee. It provides a joint-preserving option for suitable patients.

Arthrosamid treatment

Arthrosamid

As the first clinic in the UK to introduce Arthrosamid®, we bring extensive experience in providing this non-surgical option for knee osteoarthritis, focused on symptom relief and joint preservation.

PRP treatment

PRP

Platelet-rich plasma injections are particularly beneficial to those who have suffered a sport or activity related injury. The treatment contains the body’s own platelets which can promote repair.

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mFat treatment

mFat

Micro-Fragmented Adipose Tissue (MFAT) harnesses the healing capabilities of adipose-derived Stem Cell / Medicinal Signaling Cells (MSCs), offering a natural, effective solution for tissue regeneration.

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Chondroitin treatment

Chondroitin

Raw material for cartilage structure, it protects and feeds the cells. Furthermore, it can lubricate the joint, just like an oil change.

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Why Choose Us

Quickly accessible

You don’t have to wait to see one of our specialists. We prioritise efficient patient pathways.

Highest standard of care

We provide an exclusive and dedicated service that ensures you receive the best possible treatment for your needs.

Several treatment options

Multiple different treatment options both surgical and non-surgical to cover all the potential needs of our patients.

Industry professionals

Our team are at the very top of their field, having travelled the world to learn the most advanced techniques.

Cartilage Clinic London at 66 Harley Street

Location

66 Harley Street, London

Advanced Regenerative Therapy

Stem Cell / Medicinal Signaling Cell injections

Knee Stem Cell / Medicinal Signaling Cell Therapy

Knee

Stem Cell / Medicinal Signaling Cell therapy has proven to be a very effective way of treating symptoms of degenerative conditions in the knee. If you’re looking for the best possible option regardless of the cost, Stem Cell / Medicinal Signaling Cell injections could be right for you.

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Cartilage Stem Cell / Medicinal Signaling Cell Therapy

Cartilage

We specialise in utilising Mesenchymal Stem Cells / Medicinal Signaling Cells (MSCs) for the regeneration and repair of cartilage. Offering an effective, non-invasive alternative to traditional surgical methods by harnessing the body's innate ability to repair tissue.

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Shoulder Stem Cell / Medicinal Signaling Cell Therapy

Shoulder

Offering state-of-the-art shoulder therapy utilising MSCs. Our innovative approach targets the natural regeneration of shoulder joint tissues, aiming to restore mobility and reduce pain without invasive surgeries.

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Hip Stem Cell / Medicinal Signaling Cell Therapy

Hip

Our pioneering hip therapy provides non-surgical solutions using MSC regenerative capabilities. This treatment aims to enhance joint function and alleviate pain in patients experiencing chronic hip issues.

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Meet the team

Professor Paul Lee

Professor Paul Lee

Cartilage Surgeon

Leonidas Vachtsevanos

Leonidas Vachtsevanos

Consultant Orthopaedic Surgeon

Ashok Marudanayagam

Ashok Marudanayagam

Consultant Orthopaedic Surgeon

Dr. Sara McNeillis

Dr. Sara McNeillis

Consultant in Sleep Medicine and Anaesthesia

Looking for a specialist opinion?

Consult with our team to discuss the best treatment path for your condition.

Specialist Procedures

Surgical Services

Cartilage Surgery

Cartilage

Cartilage is an important part of your joints and bones and when damaged, it can lead to significant discomfort. Our surgical cartilage services include repair, regeneration, and replacement depending on which one is right for your needs.

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Meniscus Surgery

Meniscus

The meniscus is a type of cartilage located in your knee joint between your shin and thigh bone. Our surgical meniscus services include repair, partial repair, regeneration, and replacement depending on which one is right for your needs.

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Patient Testimonials

Reviews & Feedback

Athlete Spotlight

Sharron Davies & Prof Paul Lee

Hear directly from Olympian Sharron Davies about her consultation and recovery experience. A testament to our advanced, technology-driven approach to mobility and joint care.

"I had ACL surgery a few months ago and was really worried about the recovery process. A friend of mine recommended professor lee and I am so glad I followed her advice! The surgery was successful, and I recovered much faster than I expected..."

Private patient

at MSK Doctors

"Thank you, Professor, for reviewing all of my notes and going over the scans with me. I have consulted with five private orthopaedic specialists, but none of them picked up on my knee plica issue. I am very grateful for your time and expertise..."

Private patient

at MSK Doctors

"I cannot believe the incredible improvement in my knee pain since I had a meniscus repair with the biological scaffolding. Professor Lee has been amazing throughout the entire process, and I am so grateful for his expertise. Thank you!"

Private patient

at MSK Doctors

"Needed my meniscus repaired. My doctor recommended Professor Lee’s meniscus repair with cells. I am so glad I did! The treatment has been very effective in reducing my pain and improving my mobility. I would highly recommend."

Private patient

at MSK Doctors

"I should mention that I have been astounded by the results of Lipogems treatment on my knee this year. I have suffered from injuries and wear and tear (as most horse riders can attest to), and constant pain is now a thing of the past."

Private patient

at MSK Doctors

London Cartilage Clinic

Latest Insights

Clinical updates, cartilage treatment guidance, and recovery-focused articles from our specialist team.

ChondroFiller Innovations in Cartilage Repair Compared to Traditional Methods
Eleanor Hayes

ChondroFiller Innovations in Cartilage Repair Compared to Traditional Methods

Cartilage injuries pose significant challenges due to poor natural healing, with traditional treatments like debridement and microfracture often yielding limited long-term success. ChondroFiller, a novel biocompatible collagen matrix, offers a minimally invasive alternative that supports natural cartilage regeneration. Studies demonstrate its effective integration and maturation of repaired tissue, with applications extending beyond the knee to the hip joint. Compared to hyaluronic acid injections, which provide symptomatic relief without promoting tissue growth, ChondroFiller may offer more durable repair for suitable cases. Expert consultation is crucial to tailor treatments based on individual patient needs and damage extent. Emerging clinical evidence positions ChondroFiller as a promising advancement in cartilage repair, potentially improving recovery times and outcomes.

Arthrosamid Treatment for Morning Stiffness in Knee Osteoarthritis
Eleanor Hayes

Arthrosamid Treatment for Morning Stiffness in Knee Osteoarthritis

Morning stiffness in stiffness-dominant knee osteoarthritis (OA) significantly impairs mobility and daily activities. Arthrosamid, a novel injectable treatment, enhances joint lubrication and flexibility, targeting the mechanical causes of stiffness, especially after rest. Led by expert orthopaedic surgeon Professor Paul Lee at the London Cartilage Clinic, this therapy offers promising relief for those struggling with painful morning joint stiffness. By improving ease of movement, Arthrosamid may help patients regain confidence and improve their quality of life. Individuals should consult healthcare professionals to explore personalized treatment options.

The Cartledge Approach to Advanced Knee Cartilage Repair
Eleanor Hayes

The Cartledge Approach to Advanced Knee Cartilage Repair

The Cartledge approach revolutionizes knee cartilage repair by integrating biomechanics and regenerative medicine, targeting both tissue regrowth and mechanical function. This method tailors treatments based on individual joint forces, promoting the formation of durable, resilient cartilage. Supported by clinical studies, it offers improved pain relief, mobility, and longer-lasting results compared to traditional therapies. Personalized rehabilitation guided by biomechanical insights may accelerate recovery and reduce re-injury risks. Despite challenges in implementation, the Cartledge approach represents a promising future for treating knee cartilage damage, enhancing patient outcomes and quality of life through multidisciplinary innovation.