Cartilage specialists for Regeneration, Repair & Replacement

Comprehensive care for cartilage, meniscus and ACL injury, offering advanced injections, regenerative techniques and specialist surgical expertise.

Specialist Focus Areas

Focused Expertise

Providing advanced biological and surgical solutions for complex joint conditions.

Cartilage Regeneration

Cartilage Regeneration

Surgical & Non-surgical options

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Meniscus Repair

Meniscus Repair

Surgical & Non-surgical options

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ACL Repair

ACL Repair

Surgical Repair & Reconstruction

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Professor Paul Lee

Specialist Care at 66 Harley Street

Based in London’s prestigious Harley Street medical district, London Cartilage Clinic is a dedicated centre for the assessment and treatment of cartilage damage.

Led by Professor Paul Lee, our clinic specialises in cartilage and joint preservation, offering advanced, evidence-based solutions for patients seeking reliable alternatives to conventional healthcare pathways — without lengthy waiting times.

Our approach is informed by Musculoskeletal Regeneration Medicine, an interdisciplinary clinical framework combining orthopaedics, engineering, and regenerative science, and is tailored to both sports-related cartilage injuries and degenerative joint conditions.

Our Expertise

Non-Surgical Services

Chondrofiller treatment

Chondrofiller

London Cartilage Clinic is currently the only centre in the UK offering Chondrofiller®, an advanced treatment designed for focal cartilage defects in the knee. It provides a joint-preserving option for suitable patients.

Arthrosamid treatment

Arthrosamid

As the first clinic in the UK to introduce Arthrosamid®, we bring extensive experience in providing this non-surgical option for knee osteoarthritis, focused on symptom relief and joint preservation.

PRP treatment

PRP

Platelet-rich plasma injections are particularly beneficial to those who have suffered a sport or activity related injury. The treatment contains the body’s own platelets which can promote repair.

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mFat treatment

mFat

Micro-Fragmented Adipose Tissue (MFAT) harnesses the healing capabilities of adipose-derived Stem Cell / Medicinal Signaling Cells (MSCs), offering a natural, effective solution for tissue regeneration.

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Chondroitin treatment

Chondroitin

Raw material for cartilage structure, it protects and feeds the cells. Furthermore, it can lubricate the joint, just like an oil change.

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Why Choose Us

Quickly accessible

You don’t have to wait to see one of our specialists. We prioritise efficient patient pathways.

Highest standard of care

We provide an exclusive and dedicated service that ensures you receive the best possible treatment for your needs.

Several treatment options

Multiple different treatment options both surgical and non-surgical to cover all the potential needs of our patients.

Industry professionals

Our team are at the very top of their field, having travelled the world to learn the most advanced techniques.

Cartilage Clinic London at 66 Harley Street

Location

66 Harley Street, London

Advanced Regenerative Therapy

Stem Cell / Medicinal Signaling Cell injections

Knee Stem Cell / Medicinal Signaling Cell Therapy

Knee

Stem Cell / Medicinal Signaling Cell therapy has proven to be a very effective way of treating symptoms of degenerative conditions in the knee. If you’re looking for the best possible option regardless of the cost, Stem Cell / Medicinal Signaling Cell injections could be right for you.

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Cartilage Stem Cell / Medicinal Signaling Cell Therapy

Cartilage

We specialise in utilising Mesenchymal Stem Cells / Medicinal Signaling Cells (MSCs) for the regeneration and repair of cartilage. Offering an effective, non-invasive alternative to traditional surgical methods by harnessing the body's innate ability to repair tissue.

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Shoulder Stem Cell / Medicinal Signaling Cell Therapy

Shoulder

Offering state-of-the-art shoulder therapy utilising MSCs. Our innovative approach targets the natural regeneration of shoulder joint tissues, aiming to restore mobility and reduce pain without invasive surgeries.

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Hip Stem Cell / Medicinal Signaling Cell Therapy

Hip

Our pioneering hip therapy provides non-surgical solutions using MSC regenerative capabilities. This treatment aims to enhance joint function and alleviate pain in patients experiencing chronic hip issues.

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Meet the team

Professor Paul Lee

Professor Paul Lee

Cartilage Surgeon

Leonidas Vachtsevanos

Leonidas Vachtsevanos

Consultant Orthopaedic Surgeon

Ashok Marudanayagam

Ashok Marudanayagam

Consultant Orthopaedic Surgeon

Dr. Sara McNeillis

Dr. Sara McNeillis

Consultant in Sleep Medicine and Anaesthesia

Looking for a specialist opinion?

Consult with our team to discuss the best treatment path for your condition.

Specialist Procedures

Surgical Services

Cartilage Surgery

Cartilage

Cartilage is an important part of your joints and bones and when damaged, it can lead to significant discomfort. Our surgical cartilage services include repair, regeneration, and replacement depending on which one is right for your needs.

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Meniscus Surgery

Meniscus

The meniscus is a type of cartilage located in your knee joint between your shin and thigh bone. Our surgical meniscus services include repair, partial repair, regeneration, and replacement depending on which one is right for your needs.

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Patient Testimonials

Reviews & Feedback

Athlete Spotlight

Sharron Davies & Prof Paul Lee

Hear directly from Olympian Sharron Davies about her consultation and recovery experience. A testament to our advanced, technology-driven approach to mobility and joint care.

"I had ACL surgery a few months ago and was really worried about the recovery process. A friend of mine recommended professor lee and I am so glad I followed her advice! The surgery was successful, and I recovered much faster than I expected..."

Private patient

at MSK Doctors

"Thank you, Professor, for reviewing all of my notes and going over the scans with me. I have consulted with five private orthopaedic specialists, but none of them picked up on my knee plica issue. I am very grateful for your time and expertise..."

Private patient

at MSK Doctors

"I cannot believe the incredible improvement in my knee pain since I had a meniscus repair with the biological scaffolding. Professor Lee has been amazing throughout the entire process, and I am so grateful for his expertise. Thank you!"

Private patient

at MSK Doctors

"Needed my meniscus repaired. My doctor recommended Professor Lee’s meniscus repair with cells. I am so glad I did! The treatment has been very effective in reducing my pain and improving my mobility. I would highly recommend."

Private patient

at MSK Doctors

"I should mention that I have been astounded by the results of Lipogems treatment on my knee this year. I have suffered from injuries and wear and tear (as most horse riders can attest to), and constant pain is now a thing of the past."

Private patient

at MSK Doctors

London Cartilage Clinic

Latest Insights

Clinical updates, cartilage treatment guidance, and recovery-focused articles from our specialist team.

ChondroFiller Benefits for Knee Cartilage Repair
Eleanor Hayes

ChondroFiller Benefits for Knee Cartilage Repair

ChondroFiller offers a minimally invasive treatment for knee cartilage damage, promoting natural tissue regeneration and reducing recovery time. Ideal for younger, active patients with small cartilage defects, this innovative collagen-based filler supports joint health and swift healing without major surgery. Expertly administered at the London Cartilage Clinic, under Professor Paul Lee, ChondroFiller provides an effective solution for managing knee pain and mobility issues. Suitable candidates should undergo thorough clinical evaluation to ensure optimal outcomes. Early intervention with ChondroFiller can enhance quality of life by addressing cartilage damage promptly and safely.

Regenerative Gels and Standard Knee Injections for Cartilage Repair
Eleanor Hayes

Regenerative Gels and Standard Knee Injections for Cartilage Repair

Explore the differences between regenerative gels and standard knee injections for cartilage damage and knee pain. Regenerative gels like ChondroFiller Liquid promote cartilage repair and may provide longer-lasting benefits, ideal for patients with localized cartilage defects. Standard injections, such as hyaluronic acid and corticosteroids, primarily relieve symptoms and offer quicker but short-term relief. Understanding these treatment options helps patients choose the right approach for their condition. Insights from Prof. Paul Lee at the London Cartilage Clinic emphasize personalized care and informed decision-making for optimal knee health.

Articular Cartilage Structure Function and Clinical Care
Eleanor Hayes

Articular Cartilage Structure Function and Clinical Care

Articular cartilage is a specialized tissue essential for smooth joint movement, particularly in weight-bearing joints like knees and ankles. Composed mainly of collagen and proteoglycans, it absorbs shock and reduces friction but has limited self-repair due to lack of blood vessels. Injuries, often caused by trauma or aging, lead to pain and reduced mobility. Diagnosis employs MRI and sometimes arthroscopy. Treatment ranges from conservative care with physiotherapy and injections to advanced surgical methods. Emerging therapies in tissue engineering and cell-based treatments, such as iPSC-derived cartilage organoids, show promise for regeneration. The protein SOX9 plays a critical role in maintaining cartilage health and preventing degeneration. Personalized, multidisciplinary care is key for optimal recovery and joint preservation. Consulting qualified healthcare professionals ensures effective management of cartilage injuries and joint health.