Cartilage regeneration
NanoACi
A non-arthroscopic Seed, Soil and Signal pathway using an auricular-cartilage micrograft, collagen scaffold and platelet-rich fibrin.
Cartilage specialists for
Regeneration, Repair & Replacement
Tissue-first care for cartilage, meniscus, tendon and ligament damage, combining advanced regenerative pathways with specialist surgery when structure must be corrected first.
Verified across three networks
Trusted by patients on Doctify, Google and Top Doctors
Professor Lee's regenerative framework
RegenRepair™
Seed. Soil. Signal.
Start with the tissue and its mechanical job—not a generic injection. RegenRepair™ combines patient-derived biology, a collagen scaffold and a biological signal in tissue-specific pathways for cartilage, meniscus, tendon and ligament damage.
Priority treatments
The treatments patients ask about most
Four distinct options, with different targets and evidence. Suitability starts with diagnosis and imaging—not whichever name is most familiar.
Tendon regeneration
NanoATi
A tendon-specific pathway combining autologous fibroblast-rich micrografts, collagen Soil, platelet-rich fibrin Signal and progressive loading.
UK-exclusive access
ChondroFiller
An injectable, cell-free type-I collagen scaffold for selected focal cartilage defects.
Knee osteoarthritis
Arthrosamid
A single-dose polyacrylamide hydrogel injection used to treat symptoms of knee osteoarthritis.
Signature procedure
Signature procedureRepair your ACL.
Repair your ACL.
Keep your own tissue.
STARR is the cartilage-preserving ACL repair pioneered by Professor Paul Lee. No tendon graft taken from your leg, recovery in six weeks to three months, and the ligament you were born with stays where it belongs.
- No graft harvested
- 6 weeks to 3 months
- Native ligament preserved
Founder & Surgical Director
Care led by Prof Paul Lee
MBBch, FRCS (Tr & Orth), PhD · GMC 6115197
Internationally recognised cartilage surgeon, regenerative medicine doctor, and medical engineer. Founder of London Cartilage Clinic, MSK Doctors, and The Keep Clinic. Honorary Professor at the University of Lincoln, Visiting Professor at the University of Chester, Royal College of Surgeons of Edinburgh Ambassador, and Founding President of the International Association of Regenerative Medicine.
2026 · BOA
Robert Jones Medal & Association Prize
International leadership
Founding President, IAMRegen
Cartilage education
ICRS Teaching Centre of Excellence
Featured in
You may have more options than you've been told
Preserve. Repair. Regenerate. Replace.
Most patients arrive thinking the only path is replacement. We see your joint as a spectrum of choices, and replacement is the last resort, not the first.
Preserve
Protect what you still have. Targeted injections and treatments that slow cartilage wear, manage arthritis, and keep your joint working.
Repair
Fix specific damage. A torn meniscus, a damaged ligament, a kneecap problem. Procedures that restore what is broken — time matters.
Regenerate
Rebuild damaged cartilage. Advanced biological treatments that stimulate your body to grow new tissue. Several available only at London Cartilage Clinic.
Replace
When other options are exhausted, replacement restores function — but only after we have explored every alternative.
Advanced Regenerative Therapy
Stem Cell / Medicinal Signaling Cell injections
Knee
Stem Cell / Medicinal Signaling Cell therapy has proven to be a very effective way of treating symptoms of degenerative conditions in the knee. If you’re looking for the best possible option regardless of the cost, Stem Cell / Medicinal Signaling Cell injections could be right for you.
Learn More
Cartilage
We specialise in utilising Mesenchymal Stem Cells / Medicinal Signaling Cells (MSCs) for the regeneration and repair of cartilage. Offering an effective, non-invasive alternative to traditional surgical methods by harnessing the body's innate ability to repair tissue.
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Shoulder
Offering state-of-the-art shoulder therapy utilising MSCs. Our innovative approach targets the natural regeneration of shoulder joint tissues, aiming to restore mobility and reduce pain without invasive surgeries.
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Hip
Our pioneering hip therapy provides non-surgical solutions using MSC regenerative capabilities. This treatment aims to enhance joint function and alleviate pain in patients experiencing chronic hip issues.
Learn MoreKnee
Stem Cell / Medicinal Signaling Cell therapy has proven to be a very effective way of treating symptoms of degenerative conditions in the knee. If you’re looking for the best possible option regardless of the cost, Stem Cell / Medicinal Signaling Cell injections could be right for you.
Learn MoreCartilage
We specialise in utilising Mesenchymal Stem Cells / Medicinal Signaling Cells (MSCs) for the regeneration and repair of cartilage. Offering an effective, non-invasive alternative to traditional surgical methods by harnessing the body's innate ability to repair tissue.
Learn MoreShoulder
Offering state-of-the-art shoulder therapy utilising MSCs. Our innovative approach targets the natural regeneration of shoulder joint tissues, aiming to restore mobility and reduce pain without invasive surgeries.
Learn MoreHip
Our pioneering hip therapy provides non-surgical solutions using MSC regenerative capabilities. This treatment aims to enhance joint function and alleviate pain in patients experiencing chronic hip issues.
Learn MoreWhat patients say
Real stories, real patients
From an Olympian's return to movement, to everyday patients getting their pain under control, these are the outcomes we work for.
Olympian
Sharron Davies on her recovery with Prof Paul Lee
Olympian Sharron Davies talks through her consultation, treatment and return to movement, the same patient-led approach we apply to every case.
Verified patient reviews
“I had ACL surgery a few months ago and was really worried about the recovery process. A friend recommended Professor Lee and I am so glad I followed her advice. The surgery was successful, and I recovered much faster than I expected.”
Private patient
Verified
“Thank you, Professor, for reviewing all of my notes and going over the scans with me. I had consulted five private orthopaedic specialists, but none picked up on my knee plica. I am very grateful for your time and expertise.”
Private patient
Verified
“I cannot believe the incredible improvement in my knee pain since I had a meniscus repair with biological scaffolding. Professor Lee has been amazing throughout the entire process.”
Private patient
Verified
“My doctor recommended Professor Lee's meniscus repair with cells. The treatment has been very effective in reducing my pain and improving my mobility. I would highly recommend.”
Private patient
Verified
Been told you need a joint replacement?
There may be options worth exploring first. A discovery call with our team is the fastest way to find out.
Browse by body part
Find your treatment path
Each hub explains your options across all four approaches — from simple injections to advanced cartilage care.
Key surgical treatments
Specialist procedures
Cartilage
Repair, regeneration and replacement — chosen to match the size, location and depth of the defect, and your own goals.
Learn more
Meniscus
Repair, partial repair, regeneration, and replacement — keeping the meniscus where possible to protect your underlying cartilage.
Learn moreSignature
ACL repair — STARR
Cartilage-preserving ACL repair pioneered by Professor Paul Lee. No graft harvested, recovery in six weeks to three months.
Learn moreMeet the team
Looking for a specialist opinion?
Consult with our team to discuss the best treatment path for your condition.
Ready to take the next step?
Get clarity on your options
A short discovery call is the fastest way to understand what's possible for your joint — without travelling, paying, or waiting.
London Cartilage Clinic
Latest Insights
Clinical updates, cartilage treatment guidance, and recovery-focused articles from our specialist team.
Knee OA
Eleanor Hayes
Does a meniscus tear lead to arthritis?
Meniscal tears independently predict cartilage loss and osteoarthritis. Tear subtype, patient age, BMI, and alignment determine the rate of progression: posterior root tears in younger patients accelerate rapidly, whilst isolated degenerative tears may remain stable for years.
Cartilage Repair
Eleanor Hayes
ChondroFiller Injection for Elbow Cartilage Damage
ChondroFiller injection is an ultrasound-guided, outpatient treatment for focal elbow cartilage defects: a collagen scaffold recruits the patient's own progenitor cells to regenerate tissue, avoiding cell culture.
ChondroFiller / Liquid Cartilage
Eleanor Hayes
ChondroFiller vs hyaluronic acid for knee cartilage
ChondroFiller, a murine-derived collagen hydrogel, recruits the patient's own progenitor cells to repair focal cartilage lesions; hyaluronic acid viscosupplements like Durolane and Cingal restore joint lubrication in diffuse osteoarthritis without repairing tissue.