The recognised starting point
ACi and MACi
The established search terms for cell-based cartilage regeneration. Professor Lee uses them as the familiar reference point when explaining the newer non-surgical and surgical pathways.

International patients · Ireland
Irish patients travel to London Cartilage Clinic for cartilage and joint preservation, a short flight from Dublin and in a clinic that operates in English.
Read the International Patient Guide
Reviewed byProfessor Paul Lee MBBch, FRCS (Tr & Orth), PhDCartilage and joint preservation expertiseWhy London Cartilage Clinic
Ireland is close and culturally aligned, and Dublin to London is about an hour by air. Irish patients come for the depth of cartilage and joint-preservation expertise and the range of joint-preserving options.
Where suitable, a joint-preserving option is assessed rather than defaulting to replacement, at any age where the assessment supports it, strongest at the knee, with hip and other joints scoped honestly.
Why patients travel for treatment
Patients from Ireland often arrive searching for ACi or MACi because those are the best-known cartilage cell treatments. They remain important. The assessment also shows where NanoACi, the wider Nano family, the Structure-led STACi pathway, ChondroFiller or Mytocel MSK may fit more precisely.
The recognised starting point
The established search terms for cell-based cartilage regeneration. Professor Lee uses them as the familiar reference point when explaining the newer non-surgical and surgical pathways.
Non-surgical RegenRepair™
NanoACi for cartilage, NanoAMi for meniscus, NanoATi for tendon and NanoALi for ligament adapt Seed, Soil and Signal to the tissue being treated.
Surgical RegenRepair™
When alignment, stability or the damage pattern needs surgery, STACi addresses Structure before adding the Seed, Soil and Signal cartilage-regeneration biology.
Standalone or within a pathway
Mytocel MSK provides living autologous micrografts; ChondroFiller provides a collagen scaffold. Each has a standalone role and both sit within Professor Lee’s wider regenerative toolkit.
Been told replacement is your only option?
Being told replacement is the only option is often a default rather than the only path. For suitable patients, joint-preserving cartilage repair and regeneration may be an alternative, assessed on your imaging, the size and location of the damage and your goals, rather than on age alone.
The strongest case is at the knee, with hip and other joints scoped honestly and assessed case by case. It is about options, never about being faster.
Every alternative-to-replacement statement is a clinical judgement made only after a full assessment. Suitability depends on your individual case.
Most relevant treatments

The better-known cell-based cartilage regeneration procedures, kept as a clear starting point and assessed alongside NanoACi and the Structure-led STACi pathway.
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Professor Lee’s Seed, Soil, Signal framework, adapted into NanoACi for cartilage, NanoAMi for meniscus, NanoATi for tendon and NanoALi for ligament.
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A non-arthroscopic cartilage-regeneration pathway combining autologous micrografts, a collagen scaffold and platelet-rich fibrin in one image-guided session.
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Professor Lee’s surgical RegenRepair™ pathway: Structure first, then Seed, Soil and Signal for cartilage damage that needs mechanical correction or stabilisation as well as regeneration.
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Collagen cartilage regeneration delivered by injection, made by Meidrix Biomedicals GmbH. The clinic was the first in the UK to offer it as an injection.
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A single-session regenerative injection using living autologous micrografts prepared chair-side from a small sample of the patient’s own tissue.
Find out moreGetting here
Dublin to London is about an hour by air, with frequent daily flights, making a focused visit easy to plan.
About a one-hour flight to any London airport, with frequent daily services from Dublin and other Irish cities.
A discovery call and virtual consultation with Professor Lee can happen before you travel.
The clinic operates in English, so the whole pathway is easy to follow.
Visiting us
66 Harley Street
London W1G 7HD
United Kingdom
A partner hospital on Weymouth Street, a few minutes from Harley Street. Imaging is arranged for you as part of your pathway.
Central London, a short walk from Regent’s Park, Oxford Circus and Bond Street underground stations.
Costs and insurance
Treatment at London Cartilage Clinic is direct pay, quoted in pounds sterling, with your bank handling the conversion from euros.
If you hold private health insurance, treatment abroad is usually pay-and-claim-back: you settle with the clinic and claim using an itemised invoice. Confirm what your policy covers before travelling.

Authority
International patients are usually choosing between a small number of world specialists, so the surgeon matters more than any single treatment. Your consultation, your treatment and your follow-up are all with Professor Paul Lee.
International patients · Ireland
Dublin to London is about an hour by air. Many patients complete the first consultation virtually and travel only when there is a clear plan.
Suitability is assessed on your imaging, the size and location of the damage and your goals, rather than on age alone. Professor Lee is honest where a joint-preserving option is not the right choice.
Treatment is direct pay in pounds sterling. Any private insurance reimbursement is pay-and-claim-back and varies by policy, so confirm the specifics before travelling.
Wherever you are travelling from, the first step is the same. Talk it through on a discovery call, or have a virtual consultation with Professor Lee before you plan any travel.