London Cartilage Clinic IconLondon Cartilage Clinic66 Harley Street
Patient with foot joint pain and discomfort

mFat Therapy for the Foot

From £5,800
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Guide price only. Final cost is confirmed after assessment.

mFat therapy delivers adipose-derived stem cells to the affected foot joints to manage arthritis, reduce inflammation, and support cartilage preservation. Foot joint degeneration affects every step you take, and surgical options are often limited to fusion, which eliminates joint movement. Biological treatment with mFat offers a way to manage symptoms and maintain function in the foot joints that matter most for daily mobility.

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Prof Paul LeeReviewed byProf Paul LeeLast reviewed 1 May 2026
Adipose tissue harvest for mFat therapy

Why foot joints need early biological support

The foot contains over 30 joints, several of which are essential for normal gait. When arthritis develops in the big toe or midfoot, the standard surgical endpoint is joint fusion, which relieves pain but permanently removes movement.

  • The first MTP joint (big toe) is critical for push-off during walking and running.
  • Midfoot arthritis restricts the foot's ability to adapt to uneven ground.
  • Biological intervention aims to preserve movement and delay the need for fusion.

By treating foot joint degeneration earlier with mFat, patients can maintain mobility and activity levels while the biological response works to stabilise the joint environment.

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The procedure and what to expect

mFat therapy for the foot follows the same single-session protocol as other joints. The processed adipose tissue is injected directly into the affected joint under image guidance for precise delivery.

  • Outpatient procedure with local anaesthetic.
  • Multiple foot joints can be treated in the same session if needed.
  • Walking resumes within days, with gradual improvement over weeks.

Your specialist will assess which foot joints would benefit most and whether mFat alone or a combined approach with other treatments is appropriate.

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Specialist performing image-guided foot injection

You may have more options than you think

Most patients have more treatment options than they have been told

At London Cartilage Clinic we follow a structured clinical framework across four areas of treatment. Before recommending a single procedure, we assess which combination of approaches gives you the best outcome.

Preserve

Protect what you have. Slow degeneration and manage symptoms.

Repair

Fix specific damage. Torn tissue, unstable joints, structural problems.

Regenerate

Rebuild lost tissue. Biological treatments that stimulate new growth.

Replace

When other options are exhausted. Joint replacement as a last resort.

Explore the full range of treatments available for your joint. Each hub page shows every option we offer, organised by clinical approach.

Explore Foot Options
consulting-in-office-with-pen

Frequently Asked Questions

Which foot joints can be treated with mFat?

mFat therapy can be delivered to the first metatarsophalangeal joint (big toe), the midfoot joints (tarsometatarsal), and the subtalar joint. These are the joints most commonly affected by arthritis and degeneration in the foot.

Is mFat effective for big toe arthritis (hallux rigidus)?

mFat therapy can help manage the pain and stiffness of hallux rigidus by reducing inflammation and supporting the remaining cartilage. It is particularly suited to patients with early to moderate disease who want to avoid or delay fusion surgery (arthrodesis).

How does foot joint arthritis affect daily life?

The foot joints are loaded with every step. Arthritis in these joints causes pain with walking, stiffness when getting up, and difficulty wearing certain footwear. Even moderate foot joint degeneration can significantly limit mobility and overall quality of life.

What is the recovery after mFat treatment for the foot?

Most patients can walk normally within a few days, though some tenderness at the injection site and the fat harvest site is common for one to two weeks. Supportive footwear is recommended during the initial recovery period. Improvement develops gradually over the following weeks.

Still have more specific concerns?

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London Cartilage Clinic

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