Does MSC Therapy Work for Knee Cartilage Regeneration?

Does MSC Therapy Work for Knee Cartilage Regeneration?

London Cartilage Clinic

Written By London Cartilage Clinic

Knee cartilage problems, ranging from wear and tear to injuries, can significantly affect one’s quality of life by causing pain and limiting mobility. With the advancement in regenerative medicine, particularly MSC (Medicinal Signalling Cells) therapy, there’s growing interest in its potential for knee cartilage regeneration. This article explores the efficacy of MSC therapy for knee cartilage regeneration, aiming to shed light on this innovative treatment for patients seeking alternatives to traditional methods.

Understanding Knee Cartilage Regeneration

Knee cartilage regeneration refers to the process of repairing damaged cartilage in the knee joint. Cartilage is a tough, flexible tissue that covers the ends of bones in the joints, providing cushioning and enabling smooth movements. Unlike other tissues, cartilage lacks its own blood supply, making its natural repair process slow and limited.

The Role of MSC Therapy in Knee Cartilage Regeneration

MSC therapy involves the use of Medicinal Signalling Cells, previously known as stem cells, to promote tissue repair and regeneration. These cells can differentiate into a variety of tissue types, including cartilage, potentially offering a way to regenerate damaged knee cartilage. MSCs also possess anti-inflammatory properties, which can further aid in the healing process.

Purpose of MSC Therapy for Knee Cartilage

The primary purposes of MSC therapy in the context of knee cartilage include:

  • Reducing inflammation and pain in the knee joint.
  • Stimulating the regeneration of damaged cartilage tissue.
  • Improving joint function and mobility.
  • Offering a less invasive alternative to knee replacement surgery.

Alternative Treatment Options

Besides MSC therapy, several other treatment options exist for managing knee cartilage issues, such as:

  • Physical therapy and exercise to strengthen the muscles around the knee.
  • Pain relief medications, including anti-inflammatory drugs.
  • Corticosteroid or hyaluronic acid injections for temporary relief.
  • Surgical interventions, including arthroscopy, cartilage repair, and knee replacement in severe cases.

Who is a Candidate for MSC Therapy?

Candidates for MSC therapy typically include individuals with:

  • Mild to moderate cartilage damage who are seeking alternatives to surgery.
  • Chronic knee pain not adequately managed by conventional treatments.
  • A desire to explore regenerative medicine options as part of their treatment plan.

Benefits and Drawbacks of MSC Therapy



  • Potential for actual regeneration of cartilage, not just symptom management.
  • Minimally invasive procedure with fewer risks compared to surgery.
  • Reduced recovery time compared to surgical interventions.


  • Variability in treatment effectiveness between individuals.
  • Limited long-term data on the outcomes and effectiveness.
  • Potential cost implications, as treatments may not be covered by insurance.

Frequently Asked Questions

The effectiveness can vary. Some patients report significant improvements, while others may see more modest results. Ongoing research is aimed at better understanding the factors that influence treatment outcomes.

Recovery times can vary, but many patients experience minimal downtime, with some returning to normal activities within a few days to weeks after treatment.

While generally considered safe, any procedure involving injections carries potential risks, such as infection. Discussing the specific risks and benefits with a healthcare provider is essential.

The longevity of the effects can vary. Some patients report long-term relief, but additional treatments may be necessary for others.

Coverage varies widely, so it’s important to check with your insurance provider. Many regenerative medicine treatments are currently not covered by standard health insurance plans.

A thorough evaluation by a healthcare professional, preferably one specialising in regenerative medicine, is crucial to determine if MSC therapy aligns with your specific condition and treatment goals.

Cartilage Specialists

In conclusion, MSC therapy offers a promising but still developing option for knee cartilage regeneration. While it holds the potential for repairing cartilage and improving joint function, patients should carefully weigh the benefits, drawbacks, and available evidence when considering this treatment. Consulting with a healthcare provider experienced in regenerative medicine is essential to making an informed decision. At the London Cartilage Clinic, we are committed to providing our patients with the latest in orthopaedic care and regenerative medicine, helping them achieve the best possible outcomes for their knee health.

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