Regenerative medicine is a modern field of medicine based on the principle of regenerating biological tissue in the patient to replace, repair, and improve cells that have been affected by injury or disease. In order to manipulate tissue regeneration, doctors use biological scaffolds. But what are these devices and how do they work? Sports medicine specialist and expert Professor Paul Lee is here to explain:
From osteoarthritis, and sports-related cartilage injury, to meniscus injuries – scaffolding can treat various problems effectively. However, with so many different types of biological scaffolds available on the market, it is important to understand which one to use for a particular condition.Book Online
Biological scaffolds are support structures made of a specially-designed material that has a very similar structure to the human body in both mechanics and a cellular form.
They are designed to allow regeneration to happen and enable our bodies to grow into them. Think of them as a foundation for regeneration and cell therapy.
Based on the principles of regenerative medicine, biological scaffolding has been around for over 40 years. As technology has developed, our understanding of cartilage cells has improved and our ability to create micro-structures has become possible. With the latest nano 3D printing techniques it is now possible to create structures smaller than cartilage cells. These structures can guide cell growth and even affect the way they develop.
Without a clear understanding of the foundation and how it interacts with cells, it is not possible to regenerate tissue. With the latest material within the scaffold, we can enhance the power of nature and direct the cells to do what we want them to. This is why biological scaffolding is a great option.
Biological scaffolds are of great use in combination with cell therapy, for example, the 5th generation of cartilage cell treatment, and autologous chondrocyte implantation (ACI). It can be used to treat osteoarthritis, sports-related cartilage injury, and even meniscus injuries.
There are over 100 different types of biological scaffolds on the market, so it is important to understand which one to use for the condition at hand. It requires detailed biological understanding, not just a random choice based on the first page of results on a search engine.
Biological scaffolds can be used on their own or in combination with cell therapy, depending on what we are treating. Different scaffolding biomaterial or cell types can be used. We have had great success with using scaffolding treatment during keyhole surgery to treat cartilage defects.Book Online